Monthly Archives: January 2012

Tim Cantopher: Depression – the Curse of the Strong

“Anyone who gets major depression shouldn’t be ashamed. It’s a badge of pride only worn by the best people.”

Dr Tim Cantopher spoke to both branches of the Williams Project about depression: about its chemical origins in the reduction of transmitter chemicals in the limbic region of the brain, and possible evolutionary explanations for how it might have once been (and might still be) a beneficial adaptation to shut things down in unsustainable environments (lower primates have a similar “hibernation response” when things get too much). He also showed us how the effects of drugs such as alcohol are precisely reversed when used to excess. He explained how anti-depressants work, and how psychotherapy has moved somewhat from psychoanalysis into areas such as cognitive therapy. But his main point was that the kind of people who might suffer from clinical depression are driven, able, successful types who ‘go the extra mile’ – sometimes a mile or two further than is sustainable.

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Alan Dronsfield: The First World War and its Chemical Origins

Professor Alan Dronsfield, from the University of Derby, explained in an entertaining and clear lecture how in WW1 the new methods used in the industrial production of fertilisers and explosives were more important to the outcome of the war (and to the numbers of killed and wounded) than the use of the better known poison gases. The British thought they could stop the Germans producing both fertilizers and explosives by blockading  their imports of  sodium nitrate “saltpetre” from Chile, but were ignorant of the newer developments in  the German chemical industry. The process invented by Fritz Haber in 1909 to make ammonia  from nitrogen in the air and hydrogen from water provided a cheap and inexhaustible route both to nitrate fertilizers and the recently invented  “high” explosives like TNT. We learnt how they did this, and also witnessed a live demonstration of dyeing silk with madder. It was the 19th-century work on this dyestuff (crucially, carried out in Berlin), and the manufacture of a cheap synthetic version, that switched the dyestuffs industry from the UK to Germany, which then became the focus of the world’s production and, shortly later, a dynamic chemical industry that made possible the manufacture of high explosives on a huge scale. Alan’s talk was a perfect example of how two subjects can inform each other; it was also made local with photographs of the school’s WW1 memorial plaques in the chapel, and ended with images of the war accompanied by Barber’s Adagio for Strings.

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